About us

The Harris Lab uses a large repertoire of model systems and experimental approaches to understand how DNA mutating enzymes (APOBECs) provide immunity against viral infections, yet in many cases also contribute to tumor evolution through genomic DNA mutagenesis. Another goal of the Harris Lab is to translate these fundamental scientific discoveries into novel therapeutics against viruses and cancer.

Recent News

October 10, 2016
Emily Law and colleagues demonstrate the role of APOBEC3B in cancer drug resistance in the article "The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer" published in Science Advances.

September 21, 2016
A new paper by PhD. student Gabriel Starrett titled, "The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis," published in Nature Communications reveals a novel source of mutation in cancer. Links for press release: UMN News, Nature Communications

August 2016
The Harris lab welcomes two new members, Drs. Teneale Stewart and Rena Levin-Klein!

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