About us

The Harris Lab uses a large repertoire of model systems and experimental approaches to understand how DNA mutating enzymes (APOBECs) provide immunity against viral infections, yet in many cases also contribute to tumor evolution through genomic DNA mutagenesis. Another goal of the Harris Lab is to translate these fundamental scientific discoveries into novel therapeutics against viruses and cancer.

Recent News

July 2016
Ph.D. Student Gabriel Starrett along with our collaborators at the University of Alabama-Birmingham recently published the article "Functional upregulation of the DNA cytosine deaminase APOBEC3B by polyomaviruses" in the Journal of Virology.

May 2016
The Harris lab and collaborators published the article "Mutation processes in 293-based clones overexpressing the DNA cytosine deaminase APOBEC3B" in PLOS One.

March 2016
Former and current Ph.D. students Brandon Leonard and Gabriel Starrett co-authored an article entitled "APOBEC3G expression correlates with T cell infiltration and improved clinical outcomes in high-grade serous ovarian carcinoma" published in Clinical Cancer Research.

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