New Publication: Harris and Aihara groups publish the first structures of APOBEC3A-ssDNA and APOBEC3B-ssDNA in NSMB.
Gabriel Starrett wins the 2017 UMN MICaB Outstanding Graduate Student Award. Congratulations Gabe!
Dr. Reuben S. Harris recognized by UMN AHC Academies for Excellence. Congratulations!
New Publication: Emily Law and colleagues demonstrate the role of APOBEC3B in cancer drug resistance in the article "The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer" published in Science Advances.
New Publication: A new paper by PhD. student Gabriel Starrett titled, "The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis," published in Nature Communications reveals a novel source of mutation in cancer. Links for press release: UMN News, Nature Communications
Welcome to our newest lab member, Dr. Rena Levin-Klein, who has joined the lab and will be working on non-canonical APOBEC activities.
Dr. Reuben S. Harris gave a keynote presentation at the Conference on Nucleic Acids and Immunity in Brno, Czech Republic.
Welcome to our newest lab member, Dr. Teneale Stewart, who has joined the lab and will be working on APOBEC regulation.
The Harris Lab is enjoying the last days of summer by celebrating at our annual lab party. Congratulations to Emily Law for winning the bowling tournament!
New Publication: Ph.D. student Gabriel Starrett along with our collaborators Brandy Verhalen and Mengxi Jiang at the University of Alabama-Birmingham recently published the article "Functional upregulation of the DNA cytosine deaminase APOBEC3B by polyomaviruses," in the Journal of Virology.
Congratulations to Team A (Brett Anderson, Adam Cheng, Chris Richards, Brett Anderson, Dan Salamango, and Gabe Starret) for coming in second place at the First Annual Scientific Olympics!
New Publication: Dr. Nadine Shaban and our collaborators in the Aihara Lab published a paper titled, "1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure," in the Journal of Molecular Biology.
Dr. Nadine Shaban and Ph.D. student Brett Anderson presented original research at the 2016 NIH Structural Biology Related to HIV/AIDS Meeting in Bethesda, MD.
Congratulation to Dr. Daniel Salamango, who was awarded a 3-year postdoctoral fellowship from the Minnesota Craniofacial Research Training (MinnCResT) Program for his proposal on the role of APOBEC3B in HPV-induced cancers.
New Publication: The Harris lab and collaborators published the article, "Mutation processes in 293-based clones overexpressing the DNA cytosine deaminase APOBEC3B," in PLOS One.
Dr. Terumasa Ikeda gave a talk titled, "RT mutations fortify an Env-dependent mechanism that Vif-null HIV-1 can use to escape restriction by APOBEC3G," at the Cold Spring Harbor Laboratory Meeting on Retroviruses. Other lab members, Brett Anderson, Adam Cheng, Diako Ebrahimi, and Chris Richards also presented posters.
New Publication: Former and current Ph.D. students Brandon Leonard and Gabriel Starrett co-authored an article entitled, "APOBEC3G expression correlates with T cell infiltration and improved clinical outcomes in high-grade serous ovarian carcinoma," published in Clinical Cancer Research.
Congratulations to Jiayi Wang, who received the Interdisciplinary Doctoral Fellowship from the Graduate School for her proposal titled, "Delineating a Novel Barrier to HIV Transmission."
Graduate students, Brett Anderson and Jiayi Wang, presented posters at the 2016 Conference on Opportunistic Infections in Boston, MA.
Dr. Reuben Harris lectured at the University of Saskatchewan, Canada. (Link)